What is Denosyl?

Denosyl contains S-Adenosylmethionineis which is an anti-oxident that has been shown to increase hepatic Glutathione levels in the liver of dogs and cats. Glutathione is a potent antioxidant that protects the liver from toxins and death. Low liver glutathione concentrations are common in dogs and cats with decreased liver function. Denosyl's activity goes far beyond just increasing Glutathione levels. It has been shown to protect liver cells from cell death and may be useful in cell repair and healing.

S-Adenosylmethionine may also be used in other areas of tissue oxidant injury and red blood cell fragility caused by certain toxins or drugs which are related to reduced glutathione concentrations. S-Adenosylmethionine also protects liver cells from cell death and may be useful in cell regeneration. S-Adenosylmethionine may also improve bile flow in cats.

Denosyl is recommended to improve hepatic glutathione levels to help maintain and protect liver function. 45% of dogs and cats with liver problems have a low hepatic glutathione level. Denosyl has been shown to increase hepatic glutathione levels in cats and dogs. Glutathione is a potent antioxidant that protects hepatic cells.

How is Denosyl Administered?

For optimal absorption, tablets should be given orally on an empty stomach, at least one hour before feeding, as the presence of food decreases the absorption of S-Adenosylmethionine. When giving more than one tablet, the total daily dose may be provided as a morning and evening dose. For example, a daily dose of three tablets could be divided into two tablets in the morning and one tablet in the evening.

Administer a few millilitres of water immediately following any tablet administration to speed passage of the tablet into the stomach. For those owners who have difficulty administering tablets to their pets, Denosyl Tablets may be disguised in a small bite of food.

Daily administration is based on 20 mg of S-adenosylmethionine/kg bodyweight. Because the (enteric coated) tablet must be kept intact to prevent destruction by stomach acid, administration range is based on the nearest whole tablet.

Composition

90 mg Tablets (S-Adenosylmethionine 90 mg per tablet) for cats & small dogs. Up to 5.9 kg bodyweight: 1 tablet.

225 mg Tablets (S-Adenosylmethionine 225 mg per tablet) for medium dogs. 6 to 15.9 kg: 1 tablet. 16 to 29.9 kg: 2 tablets (or 1 large (425 mg) tablet).

425 mg Tablets (S-Adenosylmethionine 425 mg per tablet) for large dogs. 16 to 29.9 kg: 1 tablet (or 2 medium (225 mg) tablets). 30 to 54.9 kg: 2 tablets. Over 55 kg: 3 tablets.